Menin inhibitors for the treatment of acute myeloid leukemia: challenges and opportunities ahead

Abstract The AML treatment landscape has significantly changed in recent years with the approval of targeted therapies in the front-line and relapsed/refractory settings, including inhibitors of FLT3 and IDH1/2 mutations. More importantly, approval of the combination of the BCl-2 inhibitor, venetocl...

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Bibliographic Details
Main Authors: Kalyan V. G. Nadiminti, Kieran D. Sahasrabudhe, Hongtao Liu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-024-01632-8