Roles of Reactive Oxygen Species and Autophagy in the Pathogenesis of Cisplatin-Induced Acute Kidney Injury

Roles of Reactive Oxygen Species and Autophagy in the Pathogenesis of Cisplatin-Induced Acute Kidney Injury

Cisplatin-induced acute kidney injury (AKI) is the main factor restraining the clinical application of cisplatin. The AKI is associated with high mortality and morbidity, but no effective pharmacological treatment is available at present. As increased levels of reactive oxygen species (ROS) may prom...

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Bibliographic Details
Main Authors: Sayuri Yoshikawa, Kurumi Taniguchi, Haruka Sawamura, Yuka Ikeda, Ai Tsuji, Satoru Matsuda
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Oxygen
Subjects:
cisplatin
reactive oxygen species
autophagy
histone deacetylases
cancer
acute kidney injury
Online Access:https://www.mdpi.com/2673-9801/2/3/22

Internet

https://www.mdpi.com/2673-9801/2/3/22

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