Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy

Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy

Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Nucleolin (NCL) is a protein overexpressed and partially localized on the cell surface of tumor cells of adult cancers. Little is known about NCL and pediatric tumors and n...

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Bibliographic Details
Main Authors: Chiara Brignole, Veronica Bensa, Nuno A. Fonseca, Genny Del Zotto, Silvia Bruno, Ana F. Cruz, Fabiana Malaguti, Barbara Carlini, Fabio Morandi, Enzo Calarco, Patrizia Perri, Vera Moura, Laura Emionite, Michele Cilli, Francesco De Leonardis, Annalisa Tondo, Loredana Amoroso, Massimo Conte, Alberto Garaventa, Angela R. Sementa, Maria V. Corrias, Mirco Ponzoni, Joao N. Moreira, Fabio Pastorino
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Neuroblastoma
Cell surface protein
Nucleolin
Targeted therapy
Nanotechnology
Online Access:https://doi.org/10.1186/s13046-021-01993-9

Internet

https://doi.org/10.1186/s13046-021-01993-9

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