Polygenic association of glomerular filtration rate decline in world trade center responders

Polygenic association of glomerular filtration rate decline in world trade center responders

Abstract Background The factors associated with estimated glomerular filtrate rate (eGFR) decline in low risk adults remain relatively unknown. We hypothesized that a polygenic risk score (PRS) will be associated with eGFR decline. Methods We analyzed genetic data from 1,601 adult participants with...

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Bibliographic Details
Main Authors: Farrukh M. Koraishy, Frank D. Mann, Monika A. Waszczuk, Pei-Fen Kuan, Katherine Jonas, Xiaohua Yang, Anna Docherty, Andrey Shabalin, Sean Clouston, Roman Kotov, Benjamin Luft
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Nephrology
Subjects:
Estimated glomerular filtration rate (eGFR)
Chronic kidney disease (CKD)
Polygenic risk score (PRS)
Online Access:https://doi.org/10.1186/s12882-022-02967-5

Internet

https://doi.org/10.1186/s12882-022-02967-5

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