Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD

Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD

Abstract Background Inflammation in cardiac adipose tissue (AT) is associated with atherosclerosis. We investigated whether the epicardial-, pericardial and pre-sternal subcutaneous AT (EAT, PAT and SAT) expression of Sirtuin1 (SIRT1) and nicotinamide phosphoribosyl transferase (NAMPT) are involved...

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Bibliographic Details
Main Authors: Trine Baur Opstad, Bianca Papotti, Sissel Åkra, Charlotte Holst Hansen, Bjørn Braathen, Theis Tønnessen, Svein Solheim, Ingebjørg Seljeflot
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Subjects:
SIRT1
NAMPT
Cardiac adipose tissue
Inflammation
CHD
Online Access:https://doi.org/10.1186/s12967-023-04518-4

Internet

https://doi.org/10.1186/s12967-023-04518-4

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