By Targeting Stat3 microRNA-17-5p Promotes Cardiomyocyte Apoptosis in Response to Ischemia Followed by Reperfusion

By Targeting Stat3 microRNA-17-5p Promotes Cardiomyocyte Apoptosis in Response to Ischemia Followed by Reperfusion

Background: Several studies have confirmed the role of microRNAs in regulating ischemia/reperfusion-induced cardiac injury (I/R-I). MiR-17-5p has been regarded as an oncomiR in the development of cancer. However, its potential role in cardiomyocytes has not been exploited. The aim of this study is t...

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Bibliographic Details
Main Authors: Weijie Du, Zhenwei Pan, Xu Chen, Leimin Wang, Ying Zhang, Shuang Li, Haihai Liang, Chaoqian Xu, Yong Zhang, Yanping Wu, Hongli Shan, Yanjie Lu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-17-5p
Apoptosis
Ischemia reperfusion injury
Stat3
Online Access:http://www.karger.com/Article/FullText/366312

Internet

http://www.karger.com/Article/FullText/366312

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