How to Hit Mesenchymal Stromal Cells and Make the Tumor Microenvironment Immunostimulant Rather Than Immunosuppressive

How to Hit Mesenchymal Stromal Cells and Make the Tumor Microenvironment Immunostimulant Rather Than Immunosuppressive

Experimental evidence indicates that mesenchymal stromal cells (MSCs) may regulate tumor microenvironment (TME). It is conceivable that the interaction with MSC can influence neoplastic cell functional behavior, remodeling TME and generating a tumor cell niche that supports tissue neovascularization...

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Bibliographic Details
Main Authors: Alessandro Poggi, Serena Varesano, Maria Raffaella Zocchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stromal cells
carcinoma-associated fibroblast
tumor-associated fibroblast
tumor microenvironment
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.00262/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.00262/full

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