The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer

Abstract The activity of integrin-linked kinase (ILK) in cancerous cells is often oncogenic and associated with malignant properties, such as uncontrolled cell cycle progression and evasion from senescence. However, the role of ILK in cellular senescence in gastric cancer (GC) has not been previousl...

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Bibliographic Details
Main Authors: Chengbo Ji, Mili Zhang, Junjie Hu, Can Cao, Qisheng Gu, Youdong Liu, Xu Li, Duogang Xu, Le Ying, Yuqin Yang, Hugh Gao, Jikun Li, Liang Yu
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05020-3