Recurrent adenylation domain replacement in the microcystin synthetase gene cluster

<p>Abstract</p> <p>Background</p> <p>Microcystins are small cyclic heptapeptide toxins produced by a range of distantly related cyanobacteria. Microcystins are synthesized on large NRPS-PKS enzyme complexes. Many structural variants of microcystins are produced simulate...

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Bibliographic Details
Main Authors: Laakso Kati, Wahlsten Matti, Jokela Jouni, Rouhiainen Leo, Fewer David P, Wang Hao, Sivonen Kaarina
Format: Article
Language:English
Published: BMC 2007-10-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/7/183