Application of palladium-mediated (18)F-fluorination to PET radiotracer development: overcoming hurdles to translation.

New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated. However, progression of modern reactions from the stage of synthetic chemistry development to the preparat...

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Detalhes bibliográficos
Main Authors: Adam S Kamlet, Constanze N Neumann, Eunsung Lee, Stephen M Carlin, Christian K Moseley, Nickeisha Stephenson, Jacob M Hooker, Tobias Ritter
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3595243?pdf=render