Synthesis of 1,4-naphthoquinone derivatives using 1,3-dipolar cycloaddition and Sonogashira reactions

Synthesis of 1,4-naphthoquinone derivatives using 1,3-dipolar cycloaddition and Sonogashira reactions

Naphthoquinones are known according to their important bio-activities, such as their antitumoral and topoisomerase inhibition properties. From 2-azido (3) or 2,3-diacetylene-1,4-naphthoquinone (4) it was possible to obtain triazole derivatives (naphthoquinonic). This work describes the synthesis of...

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Bibliographic Details
Main Authors: Wilson Silva do Nascimento, Mauro Gomes da Silva, Ronaldo Nascimento de Oliveira, Celso Amorim Câmara
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2010-04-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
1
4-naphthoquinone
cycloaddition 1
3-dipolar
Sonogashira coupling
Online Access:http://www.orbital.ufms.br/index.php/dqi/article/view/161/44

Internet

http://www.orbital.ufms.br/index.php/dqi/article/view/161/44

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