In Silico Discovery of Potential Inhibitors Targeting the RNA Binding Loop of ADAR2 and 5-HT2CR from Traditional Chinese Natural Compounds

In Silico Discovery of Potential Inhibitors Targeting the RNA Binding Loop of ADAR2 and 5-HT2CR from Traditional Chinese Natural Compounds

Adenosine deaminase acting on RNA 2 (ADAR2) is an important enzyme involved in RNA editing processes, particularly in the conversion of adenosine to inosine in RNA molecules. Dysregulation of ADAR2 activity has been implicated in various diseases, including neurological disorders (including schizoph...

Full description

Bibliographic Details
Main Authors: Emmanuel Broni, Carolyn Ashley, Miriam Velazquez, Sufia Khan, Andrew Striegel, Patrick O. Sakyi, Saqib Peracha, Kristeen Bebla, Monsheel Sodhi, Samuel K. Kwofie, Adesanya Ademokunwa, Whelton A. Miller
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
adenosine deaminases acting on RNA (ADAR)
anti-ADAR2
natural products
cancer
depression
anxiety disorders
Online Access:https://www.mdpi.com/1422-0067/24/16/12612

Internet

https://www.mdpi.com/1422-0067/24/16/12612

Similar Items