Influenza vaccination and the ‘diversity paradox’

The antigenic evolution of influenza is widely assumed to occur by antigenic drift, in which strains incrementally acquire mutations in highly variable epitopes under strong immune selective pressure, such as those in the major influenza antigen haemagglutinin. However, this is not easy to reconcile...

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Bibliographic Details
Main Authors: Craig P. Thompson, Uri Obolski
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2018.1504596