Modeling Human Brain Circuitry Using Pluripotent Stem Cell Platforms

Modeling Human Brain Circuitry Using Pluripotent Stem Cell Platforms

Neural circuits are the underlying functional units of the human brain that govern complex behavior and higher-order cognitive processes. Disruptions in neural circuit development have been implicated in the pathogenesis of multiple neurodevelopmental disorders such as autism spectrum disorder (ASD)...

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Bibliographic Details
Main Authors: Annalisa M. Hartlaub, Craig A. McElroy, Nathalie L. Maitre, Mark E. Hester
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pediatrics
Subjects:
human induced pluripotent stem cell (hiPSC)
cerebral organoid
brain organoid
neurodevelopment
microfluidic
neural circuit
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00057/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2019.00057/full

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