Proteomic analysis of anti-aging effects of Dendrobium nobile Lindl. alkaloids in aging-accelerated SAMP8 mice

Proteomic analysis of anti-aging effects of Dendrobium nobile Lindl. alkaloids in aging-accelerated SAMP8 mice

Senescence-accelerated mouse prone 8 (SAMP8) mice exhibit cognitive defects and neuron loss with aging, and were used to study anti-aging effects of Dendrobium nobile alkaloids (DNLA). DNLA (20 and 40 mg/kg) were orally administered to SAMP8 mice from 6 to 10 months of age. At 10-month of age, behav...

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Bibliographic Details
Main Authors: Bo Liu, Ling-li Lv, Ping Liu, Yun-Yan Xu, Mian Guo, Jie Liu, Jing-Shan Shi
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Experimental Gerontology
Subjects:
SAMP8 and SAMR1 mice
DNLA (Dendrobium nobile Lindl. alkaloids)
Cognition
Nissl staining
Phosphorylated proteomics
Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523001195

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http://www.sciencedirect.com/science/article/pii/S0531556523001195

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