Acetylsalicylic Acid and Salicylic Acid Inhibit SARS-CoV-2 Replication in Precision-Cut Lung Slices

Acetylsalicylic Acid and Salicylic Acid Inhibit SARS-CoV-2 Replication in Precision-Cut Lung Slices

Aspirin, with its active compound acetylsalicylic acid (ASA), shows antiviral activity against rhino- and influenza viruses at high concentrations. We sought to investigate whether ASA and its metabolite salicylic acid (SA) inhibit SARS-CoV-2 since it might use similar pathways to influenza viruses....

Full description

Bibliographic Details
Main Authors: Nina Geiger, Eva-Maria König, Heike Oberwinkler, Valeria Roll, Viktoria Diesendorf, Sofie Fähr, Helena Obernolte, Katherina Sewald, Sabine Wronski, Maria Steinke, Jochen Bodem
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
acetylsalicylic acid
salicylic acid
antiviral activity
aspirin
SARS-CoV-2
precision-cut lung slices
Online Access:https://www.mdpi.com/2076-393X/10/10/1619

Internet

https://www.mdpi.com/2076-393X/10/10/1619

Similar Items