The EIF2AK4/rs4594236 AG/GG Genotype Is a Hazard Factor of Immunoglobulin Therapy Resistance in Southern Chinese Kawasaki Disease Patients

The EIF2AK4/rs4594236 AG/GG Genotype Is a Hazard Factor of Immunoglobulin Therapy Resistance in Southern Chinese Kawasaki Disease Patients

Background: Kawasaki disease (KD) is an acute, self-limited vasculitis disorder of unknown etiology in children. Immunologic abnormalities were detected during the acute phase of KD, which reflected that the effect cells of the activated immune system markedly increased cytokine production. High-dos...

Full description

Bibliographic Details
Main Authors: Hongyan Yu, Fucheng Liu, Kaining Chen, Yufen Xu, Yishuai Wang, Lanyan Fu, Huazhong Zhou, Lei Pi, Di Che, Hehong Li, Xiaoqiong Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
Kawasaki disease
IVIG resistance
polymorphism
EIF2AK4/rs4594236
intravenous immunoglobulin
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.868159/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.868159/full

Similar Items