New insights into nucleic acid sensor AIM2: The potential benefit in targeted therapy for cancer
The AIM2 inflammasome represents a multifaceted oligomeric protein complex within the innate immune system, with the capacity to perceive double-stranded DNA (dsDNA) and engage in diverse physiological reactions and disease contexts, including cancer. While originally conceived as a discerning DNA s...
Main Authors: | Jian-Zhou Cui, Zhi Huan Chew, Lina H.K. Lim |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-02-01
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Series: | Pharmacological Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661824000239 |
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