Expression of placental CD146 is dysregulated by prenatal alcohol exposure and contributes in cortical vasculature development and positioning of vessel-associated oligodendrocytes

Expression of placental CD146 is dysregulated by prenatal alcohol exposure and contributes in cortical vasculature development and positioning of vessel-associated oligodendrocytes

Recent data showed that prenatal alcohol exposure (PAE) impairs the “placenta–brain” axis controlling fetal brain angiogenesis in human and preclinical models. Placental growth factor (PlGF) has been identified as a proangiogenic messenger between these two organs. CD146, a partner of the VEGFR-1/2...

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Bibliographic Details
Main Authors: Camille Sautreuil, Maryline Lecointre, Jessica Dalmasso, Alexis Lebon, Matthieu Leuillier, François Janin, Matthieu Lecuyer, Soumeya Bekri, Stéphane Marret, Annie Laquerrière, Carole Brasse-Lagnel, Sophie Gil, Bruno J. Gonzalez
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
fetal alcohol syndrome
angiogenesis
neurovascular development
neuroplacentology
biomarker
diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1294746/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1294746/full

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