Insulin sensitizes neural and vascular TRPV1 receptors in the trigeminovascular system

Abstract Background Clinical observations suggest that hyperinsulinemia and insulin resistance can be associated with migraine headache. In the present study we examined the effect of insulin on transient receptor potential vanilloid 1 (TRPV1) receptor-dependent meningeal nociceptor functions in rat...

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Bibliographic Details
Main Authors: Judit Rosta, Máté Tóth, Nadine Friedrich, Péter Sántha, Gábor Jancsó, Mária Dux
Format: Article
Language:English
Published: BMC 2022-01-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-021-01380-x