First report of two successive deletions on chromosome 15q13 cytogenetic bands in a boy and girl: additional data to 15q13.3 syndrome with a report of high IQ patient

First report of two successive deletions on chromosome 15q13 cytogenetic bands in a boy and girl: additional data to 15q13.3 syndrome with a report of high IQ patient

Abstract 15q13.3 syndrome is associated with a wide spectrum of neurological disorders. Among a cohort of 150 neurodevelopmental cases, we identified two patients with two close proximity interstitial hemizygous deletions on chromosome 15q13. Using high-density microarrays, we characterized these de...

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Bibliographic Details
Main Authors: Maysoon Alsagob, Mustafa A. Salih, Muddathir H. A. Hamad, Yusra Al-Yafee, Jawaher Al-Zahrani, Albandary Al-Bakheet, Michael Nester, Nadia Sakati, Salma M. Wakil, Ali AlOdaib, Dilek Colak, Namik Kaya
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Cytogenetics
Subjects:
15q13.3 syndrome
Consecutive deletions
High IQ
CHRNA7
Hyperactivity
Cognitive impairment
Online Access:http://link.springer.com/article/10.1186/s13039-019-0432-6

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http://link.springer.com/article/10.1186/s13039-019-0432-6

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