Neuroprotective effect of bexarotene in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive weakness and muscle atrophy related to the loss of upper and lower motor neurons (MNs) without a curative treatment. There is experimental evidence suggesting that retinoids may be involved in ALS pathoge...

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Main Authors: Javier eRiancho, Maria eRuiz-Soto, Maria T Berciano, José eBerciano, Miguel eLafarga
格式: Article
語言:English
出版: Frontiers Media S.A. 2015-07-01
叢編:Frontiers in Cellular Neuroscience
主題:
在線閱讀:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00250/full