Piericidin A1 Blocks <italic toggle="yes">Yersinia</italic> Ysc Type III Secretion System Needle Assembly

Piericidin A1 Blocks <italic toggle="yes">Yersinia</italic> Ysc Type III Secretion System Needle Assembly

ABSTRACT The type III secretion system (T3SS) is a bacterial virulence factor expressed by dozens of Gram-negative pathogens but largely absent from commensals. The T3SS is an attractive target for antimicrobial agents that may disarm pathogenic bacteria while leaving commensal populations intact. W...

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Bibliographic Details
Main Authors: Jessica M. Morgan, Miles C. Duncan, Kevin S. Johnson, Andreas Diepold, Hanh Lam, Allison J. Dupzyk, Lexi R. Martin, Weng Ruh Wong, Judith P. Armitage, Roger G. Linington, Victoria Auerbuch
Format: Article
Language:English
Published: American Society for Microbiology 2017-02-01
Series:mSphere
Subjects:
T3SS
Yersinia
piericidin
type III secretion system
virulence blocker
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00030-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00030-17

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