Integrating unsupervised language model with triplet neural networks for protein gene ontology prediction.

Accurate identification of protein function is critical to elucidate life mechanisms and design new drugs. We proposed a novel deep-learning method, ATGO, to predict Gene Ontology (GO) attributes of proteins through a triplet neural-network architecture embedded with pre-trained language models from...

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Bibliographic Details
Main Authors: Yi-Heng Zhu, Chengxin Zhang, Dong-Jun Yu, Yang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010793