ARAP1 negatively regulates stress fibers formation and metastasis in lung adenocarcinoma via controlling Rho signaling

Abstract Small GTPases regulate multiple important cellular behaviors and their activities are strictly controlled by a mass of regulators. The dysfunction or abnormal expression of small GTPases or their regulators was frequently observed in various cancers. Here, we analyzed the expression and pro...

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Bibliographic Details
Main Authors: Zhengzheng Zhang, Wenran Xie, Bojiang Gong, Xue Liang, Hongjia Yu, Yanwen Yu, Zhixiong Dong, Fanggui Shao
Format: Article
Language:English
Published: Springer 2023-11-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00832-x