STAT3 Signaling in Breast Cancer: Multicellular Actions and Therapeutic Potential

Interleukin (IL)-6 family cytokines, such as IL-6 and IL-11, are defined by the shared use of the gp130 receptor for the downstream activation of STAT3 signaling and the activation of genes which contribute to the “hallmarks of cancer”, including proliferation, survival, invasion and metastasis. Inc...

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Bibliographic Details
Main Authors: Sarah Q. To, Rhynelle S. Dmello, Anna K. Richards, Matthias Ernst, Ashwini L. Chand
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/2/429