Evaluating the Effects of Epigallocatechin-3-Gallate on HIF-1α Protein and RORC Gene Expression in Peripheral Blood Mononuclear Cells in Patients With Multiple Sclerosis

Evaluating the Effects of Epigallocatechin-3-Gallate on HIF-1α Protein and RORC Gene Expression in Peripheral Blood Mononuclear Cells in Patients With Multiple Sclerosis

Introduction: Multiple Sclerosis (MS) is the chronic inflammation of the Central Nervous System (CNS) and autoimmune disease. MS is most widely considered to be mediated by the activation of myelin-specific T CD4+ cells as well as TH1 and TH17 cells. TH17 cells are involved in the pathogenesis of MS...

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Main Authors: Boshra Afshar, Mazdak Ganjalikhani-Hakemi, Zahra Khalifezadeh Esfahani, Nahid Eskandari, Vahid Shaygannajad, Fahimeh Hosseininasab, Freshteh Alsahebfosoul
Format: Article
Language:English
Published: Iran University of Medical Sciences 2021-07-01
Series:Basic and Clinical Neuroscience
Subjects:
multiple sclerosis
epigallocatechin-3-gallate (egcg)
rorc2
hypoxia-inducible factor 1-alpha (hif-1α)
Online Access:http://bcn.iums.ac.ir/article-1-1667-en.html

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http://bcn.iums.ac.ir/article-1-1667-en.html

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