Adjustable extracellular matrix rigidity tumor model for studying stiffness dependent pancreatic ductal adenocarcinomas progression and tumor immunosuppression

Adjustable extracellular matrix rigidity tumor model for studying stiffness dependent pancreatic ductal adenocarcinomas progression and tumor immunosuppression

Abstract Pancreatic ductal adenocarcinomas (PDAC) is one of the stiffest malignancies with strong solid stresses. Increasing stiffness could alter cellular behavior and trigger internal signaling pathways and is strongly associated with a poor prognosis in PDAC. So far, there has been no report on o...

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Bibliographic Details
Main Authors: Haoxiang Zhang, Jiaoshun Chen, Xiaoqing Hu, Jianwei Bai, Tao Yin
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Bioengineering & Translational Medicine
Subjects:
extracellular matrix rigidity
gelatin methacryloyl
hydrogels
pancreatic cancer
tumor immunosuppression
Online Access:https://doi.org/10.1002/btm2.10518

Internet

https://doi.org/10.1002/btm2.10518

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