Systematic Engineering of <i>Saccharomyces cerevisiae</i> for the De Novo Biosynthesis of Genistein and Glycosylation Derivatives

Isoflavones are predominantly found in legumes and play roles in plant defense and prevention of estrogen-related diseases. Genistein is an important isoflavone backbone with various biological activities. In this paper, we describe how a cell factory that can de novo synthesize genistein was constr...

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Bibliographic Details
Main Authors: Yongtong Wang, Zhiqiang Xiao, Siqi Zhang, Xinjia Tan, Yifei Zhao, Juan Liu, Ning Jiang, Yang Shan
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/10/3/176