TGF-β1 Reduces Neutrophil Adhesion and Prevents Acute Vaso-Occlusive Processes in Sickle Cell Disease Mice
Sickle cell disease (SCD) patients experience chronic inflammation and recurrent vaso-occlusive episodes during their entire lifetime. Inflammation in SCD occurs with the overexpression of several inflammatory mediators, including transforming growth factor beta-1 (TGF-β1), a major immune regulator....
Main Authors: | Lidiane S. Torres, Hanan Chweih, Fernanda C. Z. Fabris, Erica M. F. Gotardo, Flávia C. Leonardo, Sara T. Olalla Saad, Fernando F. Costa, Nicola Conran |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/7/1200 |
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