Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway

Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway

Summary: Linear nevus sebaceous syndrome (LNSS) is a neurocutaneous disorder caused by somatic gain-of-function mutations in KRAS or HRAS. LNSS brains have neurodevelopmental defects, including cerebral defects and epilepsy; however, its pathological mechanism and potentials for treatment are largel...

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Bibliographic Details
Main Authors: Ye Eun Kim, Yong-Seok Kim, Hee-Eun Lee, Ki Hurn So, Youngshik Choe, Byung-Chang Suh, Joung-Hun Kim, Sang Ki Park, Gary W. Mathern, Joseph G. Gleeson, Jong-Cheol Rah, Seung Tae Baek
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723000141

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http://www.sciencedirect.com/science/article/pii/S2211124723000141

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