Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD

Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD

Cigarette smoke (CS) is the most common risk factor for chronic obstructive pulmonary disease (COPD). The present study aimed to elucidate whether mtDNA is released upon CS exposure and is detected in the plasma of former smokers affected by COPD as a possible consequence of airway damage. We measur...

Full description

Bibliographic Details
Main Authors: Luca Giordano, Alyssa D. Gregory, Mireia Pérez Verdaguer, Sarah A. Ware, Hayley Harvey, Evan DeVallance, Tomasz Brzoska, Prithu Sundd, Yingze Zhang, Frank C. Sciurba, Steven D. Shapiro, Brett A. Kaufman
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
cigarette smoke
COPD
mitochondria
cell-free DNA
oxidative stress
senescence
Online Access:https://www.mdpi.com/2073-4409/11/3/369

Internet

https://www.mdpi.com/2073-4409/11/3/369

Similar Items