Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases

Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases

Purpose: Mitochondrial dysfunction is central to breaking the barrier integrity of retinal endothelial cells (RECs) in various blinding eye diseases such as diabetic retinopathy and retinopathy of prematurity. Therefore, we aimed to investigate the role of different mitochondrial constituents, speci...

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Bibliographic Details
Main Authors: Shaimaa Eltanani, Thangal Yumnamcha, Andrew Gregory, Mahmoud Elshal, Mohamed Shawky, Ahmed S. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
human retinal endothelial cells (HRECs)
rotenone
oligomycin
FCCP
oxidative phosphorylation
OxPhos
Online Access:https://www.mdpi.com/2073-4409/11/24/4128

Internet

https://www.mdpi.com/2073-4409/11/24/4128

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