The recognition of N-glycans by the lectin ArtinM mediates cell death of a human myeloid leukemia cell line.

ArtinM, a D-mannose-binding lectin from Artocarpus heterophyllus (jackfruit), interacts with N-glycosylated receptors on the surface of several cells of hematopoietic origin, triggering cell migration, degranulation, and cytokine release. Because malignant transformation is often associated with alt...

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Bibliographic Details
Main Authors: Fernanda Caroline Carvalho, Sandro Gomes Soares, Mirela Barros Tamarozzi, Eduardo Magalhães Rego, Maria-Cristina Roque-Barreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3223207?pdf=render