Magnesium Orotate Influence on Thoracic Aorta in Laboratory Rabbits Receiving Levofloxacin

Magnesium Orotate Influence on Thoracic Aorta in Laboratory Rabbits Receiving Levofloxacin

Scientific relevance. Fluoroquinolones are antibacterial agents associated with adverse drug reactions (ARDs), including aortic lesions; this ARD risk limits the use of fluoroquinolones. Moreover, fluoroquinolones have been reported to induce lesions in other connective tissues (cartilage, tendons),...

Full description

Bibliographic Details
Main Authors: N. V. Izmozherova, D. V. Zaytsev, V. V. Bazarny, V. M. Bakhtin, L. G. Polushina, M. A. Kopenkin, D. V. Tolstykh, E. A. Mukhlynina
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2022-03-01
Series:Безопасность и риск фармакотерапии
Subjects:
fluoroquinolones
levofloxacin
magnesium
magnesium orotate
aorta
matrix metalloproteinase
tissue inhibitor of matrix metalloproteinase
rabbits
tensile test
non-clinical study
Online Access:https://www.risksafety.ru/jour/article/view/393

Internet

https://www.risksafety.ru/jour/article/view/393

Similar Items