Immunohistochemical analysis of Tn antigen expression in colorectal adenocarcinoma and precursor lesions

Immunohistochemical analysis of Tn antigen expression in colorectal adenocarcinoma and precursor lesions

Abstract Background The Tn antigen (CD175) is an O-glycan expressed in various types of human adenocarcinomas, including colorectal cancer (CRC), though prior studies have relied heavily upon poorly characterized in-house generated antibodies and lectins. In this study, we explored Tn expression in...

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Bibliographic Details
Main Authors: Gabrielle E. Dombek, Ana Sofia Ore, Jane Cheng, Yasuyuki Matsumoto, Jonathan N. Glickman, Aaron Fleishman, Jamie Heimburg-Molinaro, Vitaliy Y. Poylin, Anne Fabrizio, Thomas Cataldo, Evangelos Messaris, Richard D. Cummings
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Cancer
Subjects:
Tn antigen
STn antigen
Colorectal Cancer
Transitional Margin
Immunohistochemistry
Anti-Tn antibody
Online Access:https://doi.org/10.1186/s12885-022-10376-y

Internet

https://doi.org/10.1186/s12885-022-10376-y

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