Computational formulation of a multiepitope vaccine unveils an exceptional prophylactic candidate against Merkel cell polyomavirus

Computational formulation of a multiepitope vaccine unveils an exceptional prophylactic candidate against Merkel cell polyomavirus

Merkel cell carcinoma (MCC) is a rare neuroendocrine skin malignancy caused by human Merkel cell polyomavirus (MCV), leading to the most aggressive skin cancer in humans. MCV has been identified in approximately 43%–100% of MCC cases, contributing to the highly aggressive nature of primary cutaneous...

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Bibliographic Details
Main Authors: Raihan Rahman Imon, Abdus Samad, Rahat Alam, Ahad Amer Alsaiari, Md. Enamul Kabir Talukder, Mazen Almehmadi, Foysal Ahammad, Farhan Mohammad
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
Merkel cell polyomavirus (MCV)
Merkel cell carcinomas (MCC)
immunoinformatics
vaccine design
multiepitope vaccine
molecular dynamics simulation (MD)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1160260/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1160260/full

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