Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer

Abstract Transposable elements (TEs) are prevalent repeats in the human genome, play a significant role in the regulome, and their disruption can contribute to tumorigenesis. However, TE influence on gene expression in cancer remains unclear. Here, we analyze 275 normal colon and 276 colorectal canc...

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Váldodahkkit: Nikolaos M. R. Lykoskoufis, Evarist Planet, Halit Ongen, Didier Trono, Emmanouil T. Dermitzakis
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2024-01-01
Ráidu:Nature Communications
Liŋkkat:https://doi.org/10.1038/s41467-023-42405-0