USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription.

The interplay between polycomb and trithorax complexes has been implicated in embryonic stem cell (ESC) self-renewal and differentiation. It has been shown recently that WRD5 and Dpy-30, specific components of the SET1/MLL protein complexes, play important roles during ESC self-renewal and different...

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Main Authors: Changwang Deng, Ying Li, Shermi Liang, Kairong Cui, Tal Salz, Hui Yang, Zhanyun Tang, Patrick G Gallagher, Yi Qiu, Robert Roeder, Keji Zhao, Jörg Bungert, Suming Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3675019?pdf=render