Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos

Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos

Introduction: Several healthy euploid births have been reported following the transfer of mosaic embryos, including both euploid and aneuploid blastomeres. This has been attributed to a reduced number of aneuploid cells, as previously reported in mice, but remains poorly explored in humans. We hypot...

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Bibliographic Details
Main Authors: Akifumi Ijuin, Hiroe Ueno, Tomonari Hayama, Shunsuke Miyai, Ai Miyakoshi, Haru Hamada, Sumiko Sueyoshi, Shiori Tochihara, Marina Saito, Haruka Hamanoue, Teppei Takeshima, Yasushi Yumura, Etsuko Miyagi, Hiroki Kurahashi, Hideya Sakakibara, Mariko Murase
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mosaic embryo
mitochondria
mitochondrial DNA mutation
aneuploid cell decrease
post-implantation development
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1215626/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1215626/full

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