Designing a Topical Nanoliposomal Formulation of Ruxolitinib Phosphate

Designing a Topical Nanoliposomal Formulation of Ruxolitinib Phosphate

Background: The JAK-STAT pathway has been revealed to play a crucial role in the dysregulation of immune responses in autoimmune skin disorders. Ruxolitinib, a selective inhibitor of JAK1 and JAK2, potently suppresses cytokine signaling. Methods: A topical emulgel containing ruxolitinib nanoliposom...

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Bibliographic Details
Main Authors: Atefeh Naeimifar, Saman Ahmad Nasrollahi, Hamid Akbari Javar, Mansoor Nassiri Kashani, Alireza Firooz, Mohamadreza Rouini
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-01-01
Series:Pharmaceutical Sciences
Subjects:
autoimmune dermatological disorders
cytokine signaling
dsc
nanoliposomes
ruxolitinib
sem
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-29-75.pdf

Internet

https://ps.tbzmed.ac.ir/PDF/ps-29-75.pdf

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