Association of HTRA1 and ARMS2 gene polymorphisms with response to intravitreal ranibizumab among neovascular age-related macular degenerative subjects

Association of HTRA1 and ARMS2 gene polymorphisms with response to intravitreal ranibizumab among neovascular age-related macular degenerative subjects

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Abstract Background The association of HTRA1 rs11200638 and ARMS2 rs10490924 gene polymorphisms with response to intravitreal ranibizumab therapy among neovascular AMD (nAMD) subjects in Malaysia was determined in this study, followed by the expression of HTRA1 and ARMS2 genes. Results Both single n...

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Bibliographic Details
Main Authors: Nur Afiqah Mohamad, Vasudevan Ramachandran, Hazlita Mohd Isa, Yoke Mun Chan, Nor Fariza Ngah, Siew Mooi Ching, Fan Kee Hoo, Wan Aliaa Wan Sulaiman, Liyana Najwa Inche Mat, Mohd Hazmi Mohamed
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Human Genomics
Subjects:
Age-related macular degeneration
Age-related maculopathy susceptibility 2
High temperature requirement a serine peptidase 1
Polymorphism
Ranibizumab
Online Access:http://link.springer.com/article/10.1186/s40246-019-0197-3

Internet

http://link.springer.com/article/10.1186/s40246-019-0197-3

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