Fgf-signaling is compartmentalized within the mesenchyme and controls proliferation during salamander limb development

Although decades of studies have produced a generalized model for tetrapod limb development, urodeles deviate from anurans and amniotes in at least two key respects: their limbs exhibit preaxial skeletal differentiation and do not develop an apical ectodermal ridge (AER). Here, we investigated how S...

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Bibliographic Details
Main Authors: Sruthi Purushothaman, Ahmed Elewa, Ashley W Seifert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/48507