In silico approach for the development of phenolic derivatives as potential anti-angiogenic agents against lysyl oxidase-like 2 enzyme

In silico approach for the development of phenolic derivatives as potential anti-angiogenic agents against lysyl oxidase-like 2 enzyme

Abstract Background Lysyl oxidase-like 2 (LOXL2) has recently been explored as extremely pivotal protein involved in angiogenesis which results in metastasis of numerous types of cancers. Hence, LOXL2 is an exciting new target for drug development against tumor progression and its spread to distant...

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Bibliographic Details
Main Authors: Muhammad Tahir Aqeel, Nisar-Ur-Rahman, Arif-ullah Khan, Zaman Ashraf, Samiullah Khan, Muazzam Arif
Format: Article
Language:English
Published: SpringerOpen 2022-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Anti-angiogenic
Lysyl oxidase-like 2
Phenolic derivatives
MD simulation
In silico
Online Access:https://doi.org/10.1186/s43094-022-00422-8

Internet

https://doi.org/10.1186/s43094-022-00422-8

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