Potent and Broad-Spectrum Bactericidal Activity of a Nanotechnologically Manipulated Novel Pyrazole

Potent and Broad-Spectrum Bactericidal Activity of a Nanotechnologically Manipulated Novel Pyrazole

The antimicrobial potency of the pyrazole nucleus is widely reported these days, and pyrazole derivatives represent excellent candidates for meeting the worldwide need for new antimicrobial compounds against multidrug-resistant (MDR) bacteria. Consequently, 3-(4-chlorophenyl)-5-(4-nitrophenylamino)-...

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Bibliographic Details
Main Authors: Silvana Alfei, Debora Caviglia, Alessia Zorzoli, Danilo Marimpietri, Andrea Spallarossa, Matteo Lusardi, Guendalina Zuccari, Anna Maria Schito
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
Subjects:
CR232-loaded dendrimer NPs
3-(4-chlorophenyl)-5-(4-nitrophenylamino)-1H-pyrazole-4-carbonitrile (CR232)
Gram-positive and Gram-negative MDR isolates
MICs and MBCs
time-kill experiments
cytotoxicity on human cells
Online Access:https://www.mdpi.com/2227-9059/10/4/907

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https://www.mdpi.com/2227-9059/10/4/907

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