A novel humanized mouse model for HIV and tuberculosis co-infection studies

A novel humanized mouse model for HIV and tuberculosis co-infection studies

BackgroundTuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to be a major public health problem worldwide. The human immunodeficiency virus (HIV) is another equally important life-threatening pathogen. HIV infection decreases CD4+ T cell levels markedly increasing Mtb co-infec...

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Bibliographic Details
Main Authors: José Alejandro Bohórquez, Sitaramaraju Adduri, Danish Ansari, Sahana John, Jon Florence, Omoyeni Adejare, Gaurav Singh, Nagarjun V. Konduru, Chinnaswamy Jagannath, Guohua Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Immunology
Subjects:
humanized mouse model
HIV
Mycobacterium tuberculosis
NSG-SGM3 mice
HIV/Mtb-induced immunopathogenesis
HIV/Mtb-differentiated metabolites
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1395018/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1395018/full

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