Role of circadian gene Clock during differentiation of mouse pluripotent stem cells

Role of circadian gene Clock during differentiation of mouse pluripotent stem cells

Abstract Biological rhythms controlled by the circadian clock are absent in embryonic stem cells (ESCs). However, they start to develop during the differentiation of pluripotent ESCs to downstream cells. Conversely, biological rhythms in adult somatic cells disappear when they are reprogrammed into...

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Bibliographic Details
Main Authors: Chao Lu, Yang Yang, Ran Zhao, Bingxuan Hua, Chen Xu, Zuoqin Yan, Ning Sun, Ruizhe Qian
Format: Article
Language:English
Published: Oxford University Press 2016-09-01
Series:Protein & Cell
Subjects:
Circadian gene Clock
mouse embryonic stem cells
gene knockout
pluripotency
cell proliferation
cell apoptosis
Online Access:http://link.springer.com/article/10.1007/s13238-016-0319-9

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http://link.springer.com/article/10.1007/s13238-016-0319-9

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