A study of The Frequency and Type of Mutation in Exon 11 in BRCA1 and BRCA2 Genes In Breast Cancer Women With Positive Family History

Background:Both BRCA1 and BRCA2 are tumor suppressor gene and are inherited as an autosomal dominant. The cumulative lifetime risk of developing invasive breast cancer for those with BRCA1 or BRCA2 mutations ranges from 53% to 89%. Familial breast cancer represent less than 10% of all cancers of th...

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Bibliographic Details
Main Authors: Noor Jassim M, Ammar Ahmed Sultan, Fhadil Ahmed Dalaf
Format: Article
Language:English
Published: College of medicine/ University of Diyala 2018-06-01
Series:Diyala Journal of Medicine
Subjects:
Online Access:https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/38