In silico detection of sequence variations modifying transcriptional regulation.

In silico detection of sequence variations modifying transcriptional regulation.

Identification of functional genetic variation associated with increased susceptibility to complex diseases can elucidate genes and underlying biochemical mechanisms linked to disease onset and progression. For genes linked to genetic diseases, most identified causal mutations alter an encoded prote...

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Bibliographic Details
Main Authors: Malin C Andersen, Pär G Engström, Stuart Lithwick, David Arenillas, Per Eriksson, Boris Lenhard, Wyeth W Wasserman, Jacob Odeberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18208319/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18208319/?tool=EBI

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