Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness.

OBJECTIVE:The combined thickness of the intima and media of the carotid artery (carotid intima-medial thickness, CIMT) is associated with cardiovascular disease and stroke. Previous studies indicate that carotid intima-medial thickness is a significantly heritable phenotype, but the responsible gene...

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Bibliographic Details
Main Authors: Thahira J Rahman, Elizabeth A Walker, Bongani M Mayosi, Darroch H Hall, Peter J Avery, John M C Connell, Hugh Watkins, Paul M Stewart, Bernard Keavney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3155541?pdf=render